The CYP46A1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CYP46A1. This antibody recognizes Human antigen. The CYP46A1 Antibody has been validated for the following applications: Immunohistochemistry, and Western Blot.
Description
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism